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Dergi Kimliği

Online ISSN (İngilizce)
1305-3124

Basılı ISSN (Türkçe)
1300-5251

Online ISSN (Türkçe)
1305-3132

Kuruluş
1993

Editör
Cihat Şen

Yardımcı Editörler
Murat Yayla, Oluş Api

Predictive role of the neutrophil to lymphocyte ratio and platelet to lymphocyte ratio for diagnosis of acute appendicitis during pregnancy

Fatih Mehmet Yazar, Murat Bakacak, Arif Emre, Aykut Urfalıoğlu, Salih Serin, Emrah Cengiz, Ertan Bülbüloğlu

Künye

Predictive role of the neutrophil to lymphocyte ratio and platelet to lymphocyte ratio for diagnosis of acute appendicitis during pregnancy. Perinatoloji Dergisi 2015;23(3):S71 DOI: 10.2399/prn.15.S001084

Yazar Bilgileri

Fatih Mehmet Yazar1,
Murat Bakacak1,
Arif Emre1,
Aykut Urfalıoğlu1,
Salih Serin2,
Emrah Cengiz1,
Ertan Bülbüloğlu1

  1. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Kahramanmaraş
  2. Tatvan Devlet Hastanesi, Bitlis
Yazışma Adresi

Salih Serin, Tatvan Devlet Hastanesi, Bitlis , opdrsalihserin@gmail.com

Yayın Geçmişi

Gönderilme Tarihi: 30 Ağustos 2015

Son Revizyon Tarihi: 30 Ağustos 2015

Kabul Edilme Tarihi: 01 Eylül 2015

Erken Baskı Tarihi: 01 Ekim 2015

Yayınlanma Tarihi: 01 Ekim 2015

Çıkar Çakışması

Çıkar çakışması bulunmadığı belirtilmiştir.

Amaç
Acute appendicits (AA), a leading pathology requiring surgery in the pregnancy period is an inflammatory condition with difficulties in diagnosis. There are studies in the literature reporting that Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are early markers of local or systemic inflammation. Objective of this study was to evaluate predictive affects of NLR and PLR in addition to the conventional diagnostic methods in acut appendicitis.
Yöntem
In this study; age, gestational age, lymphocyte number, Alvarado scores (AS), levels of C-reactive protein, NLR and PLR values were studied in 28 patients operated due to AA (Appendectomy Group), 35 patients hodpitalized with the suspection of AA and considered not to have appendicitis in the follow-up (Expectant Group), 29 healthy pregnants (Healty Pregnant Control Group) and 30 non-pregnant healthy patients (Healty Women Control group).
Bulgular
Mean WBC count and CRP level were higher in the Appendectomy than in the control group (p<0.05 and p<0.05; respectively). Similarly median NLR and PLR levels were found to be statistically significantly different in the appendectomy group compared to all of the other groups (p<0.05 and p<0.05; respectively). Cut-off values were calculated with ROC analysis for WBC count (13880, p=0.030), CRP (10.1, p<0.001), lymphocyte count (1.54, p<0.001), NLR (6.84, p<0.001) and PLR (121.78, p<0.001). When WBC count, CRP, lymphocyte count, NLR and PLR were assessed with Multiple Logistic Regression analysis, it was found that accurate diagnosis of AA could be established with the combined use of these variable parameters with 90.5% accuracy.
Sonuç
In addition to the routine diagnostic methods, NLR and PLR could increase the accuracy in diagnosis of appendicitis in pregnants. 
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