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Dergi Kimliği

Online ISSN (İngilizce)
1305-3124

Basılı ISSN (Türkçe)
1300-5251

Online ISSN (Türkçe)
1305-3132

Kuruluş
1993

Editör
Cihat Şen

Yardımcı Editörler
Murat Yayla, Oluş Api

The evaluation of nesfatin-1 levels in patients with and without intrauterine growth restriction

Salih Serin, Murat Bakacak, Deniz C Arıkan

Künye

The evaluation of nesfatin-1 levels in patients with and without intrauterine growth restriction. Perinatoloji Dergisi 2015;23(3):S52 DOI: 10.2399/prn.15.S001084

Yazar Bilgileri

Salih Serin1,
Murat Bakacak2,
Deniz C Arıkan2

  1. Tatvan Devlet Hastanesi, Bitlis
  2. Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Kahramanmaraş
Yazışma Adresi

Salih Serin, Tatvan Devlet Hastanesi, Bitlis, opdrsalihserin@gmail.com

Yayın Geçmişi

Gönderilme Tarihi: 30 Ağustos 2015

Son Revizyon Tarihi: 30 Ağustos 2015

Kabul Edilme Tarihi: 01 Eylül 2015

Erken Baskı Tarihi: 01 Ekim 2015

Yayınlanma Tarihi: 01 Ekim 2015

Çıkar Çakışması

Çıkar çakışması bulunmadığı belirtilmiştir.

Amaç
To evaluate nesfatin-1 levels in patients with and without intrauterine growth restriction and to analyze the correlation between nesfatin-1 levels and fetal birth weights.
Yöntem
The study comprised a total of 81 cases; 41 patients with IUGR and 40 healthy cases. Demographic data, pregnancy weeks, fetal birth weights and nesfatin-1 levels were all recorded. The nesfatin-1 levels were compared between the groups and the correlation between fetal birth weights and nesfatin-1 levels was analyzed.
Bulgular
No statistical significant difference was determined between the groups in terms of demographic data (p>0.05). Average birth weights were determined as 3420±259 g in the control group and 2041±350 g in the IUGR group, which was found to be statistically unequal (p=0.001). The average nesfatin levels in the control group were 0.069±0.011, and 0.094±0.042 in the IUGR group. This difference was statistically unequal (p=0.001). While no correlation was determined between nesfatin levels and fetal birthweights in the control group (r=-0.034 ve p=0.836), in the IUGR group and when all the cases were evaluated together, a statistically moderately significant negative correlation was determined (r=-0.469, p=0.002 and r=-0.251, p=0.024 respectively).
Sonuç
Although intrauterine growth is a multifactorial process, the effect mechanism has not yet been established. The results of this study offer some indications about the possible effect of nesfatin-1 on fetal growth.
Anahtar Kelimeler