Maternal mortality due to amniotic embolism

B. Kilasonia

Künye

Maternal mortality due to amniotic embolism. Perinatoloji Dergisi 2002;10(3):185-186

Yazar Bilgileri

B. Kilasonia

Tblisi State Medical University Department of Forensic Medicine Tblisi GE

Yazışma Adresi

B. Kilasonia, Tblisi State Medical University Department of Forensic Medicine Tblisi GE,

Yayın Geçmişi

Çıkar Çakışması

Çıkar çakışması bulunmadığı belirtilmiştir.

The cause of sudden and unexpected death of mother in normal pregnaney, delivery and postnatal period is difficult to estimate. Among the possible causes the leading role belongs to death due to amniotic embolism.
To study pathogenesis and pathomorphological changes of amniotic embolism, had been invesligaled 9 cases of death due to amniotic embolism and 26 cases of death due to bleeding from uterus. Experimental study was performed on 55 adult healthy female rabbits. The animals had been divided into four groups: I - control group; II - with injection of filtrated amniotic fluid into the auricular marginal vein; III -with injection of not-filtrated but clear amniotic fluid; IV - with injection of not-filtrated and not-clear amniotic fluid.

The study of dissection and experimental material revealed that obstetrical coagulopathic bleedings in majority of cases a re the complications of amniotic embolism. The experimental study showed different clinical variants of amniotic embolism: 1. İnfusion of filtrated amniotic fluid with mild picture, causes the anaphylactic reaction, discirculatory and coagulopathic changes, and only rarely causes the death. 2. Infusion of not-filtrated but clear amniotic fluid causes embolic discirculatory processes in lungs together with allergic damages and intensive coagulopathic changes - equal to clinical obstetrical chock with collapse and later afibrinogemical bleeding. 3. Embolism with contaminated amniotic fluid always causes the death and resembles to those clinical cases wilh true diagnosis "Amniotic Embolism", when the cause of death is allergic reaction complicated by embolic discirculatory processes in lungs.