Oxitocinone, inducting fetus maturation

The aim of this study was to present the possibility of making earlier maturation of fetus lungs, by provocating the "stress phenomena".

Yöntem

In the last three months, we started an interesting study of provocating faster produetion of lecitin L and sphingomieline S in fetus lungs by giving mothers the infusions of sintocinone in the course of 7 days, in low doses, looking after cardiothocography, ultrasound and doppler, and making the analysis of L/S ration after and before the experiment.

Bulgular

 We have tested 30 women between 35wg-37wg, with diabetes mellitus gestational in 24 of them and insulin dependent in 3 cases. The L/S ratio was 1,5/1 and they had 0,7-1,1 xl0 cells. After 5-7 days of oxitocinone infusions at 6-8 hours intervals in 0,9%NaCl solutions we have checked their ansimes concentration and in 87% (26 cases) it was for planning delivery, L/S=2/l and we had 1,2 to 2,1 x 10 cells. in 13% the L/S ratio was 1,75/1 and it is nearly enough for delivery.

Sonuç

 We wanted to suggest a possible way of speeding fetus lung maturation, using oxitocinone infusions and initialing stimulus to realise endogenous TRH and T3, by making fluetuations in fetus PO2. This is a pilot idea, but very successful, and needs more experience.

Anahtar Kelimeler

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