Early postpartum detection of hepatitis b surface antigen

Neonates of women positive for Hepatitis B surface Antigen (HBsAg) are at risk of becoming chronically infected, which can lead to significant future health disorders such as hepatocellular carcinoma. Without treatment 65% to 90% of these newborns will become chronic carriers. The purpose of this study was to find out the carriers at early postpartum period who were not detected for Hepatitis B during pregnaney and to prevent the newborns.

Yöntem

A prospective study was developed at Department of Obstetrics and Gynecology of Harran University Hospital between June 2001 and June 2002. 136 pregnant women who attended to the delivery room and their newborns included to the study. The mean age of the cases was 27.4(SD 4.9) years. Blood samples of mothers and newborns were collected at the first 2 hours of the birth. The samples were analyzed for HbsAg and Hepatitis B Antibodies (HbsAb). SPSS 11.02 for Windows was used for statistical analyzes.

Bulgular

A total of 10 (7.3%) HBsAg-positive mother were identified. Fifty-six mothers (41.1%) had HbsAb. Forty-three (31.6%) of the newborns had HbsAb but all were negative for HbsAg and 95 (68.4%>) newborns were seronegative. infants born to HbsAg-positive mothers hepatitis B-specific immune globulin (HBIg) and hepatitis vaccine were used.

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Anahtar Kelimeler

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