Serum uric acid measurements in hypertensive disorders of pregnancy

Relation between serum uric acid levels and hypertensive disorders of pregnancy was suggested by some authors. in this study we investrgated serum uric acid levels and clinical findings of pregnant women with hypertensive disorders. The study population consisted of 46 healthy pregnant women as a control group, 122 women with pregnancy induced hypertension (PIH), 25 women with chronic hypertension and 31 women with chronic hypertension and superimposed preeclampsia. Mean age and parity were significantly lower in control and PIH groups. Mean gestational age and mean birth weight were significantly higher in the control group than the others, because of pregnancy interruptions in the hypertensive pregnant due to fetal distress. Serum uric acid and creatinin levels were significantly elevated in hypertensive pregnant. There was no significant difference in mean uric acid levels between various hypertensive disorders. As a conclusion, serum uric acid levels may be useful in follow up of pregnant with hypertensive disorders but can not be used for differentiating various hypertensive disorders of pregnancy.