Effect of parity on first trimester uterine artery doppler flow velocity and waveforms. Perinatoloji Dergisi 2011;19(2):90-90
- Haseki Training and Research Hospital Department of Obstetrics and Gynecology, Division of Perinatology İstanbul TR
Banu Dane, Haseki Training and Research Hospital Department of Obstetrics and Gynecology, Division of Perinatology İstanbul TR,
Çıkar çakışması bulunmadığı belirtilmiştir.
To investigate the relationship between first trimester uterine artery Doppler findings, maternal age and parity in our pregnant population
Uterine artery Doppler studies were performed in singleton pregnancies at 11-14 weeks of gestation. Cases with fetal chromosomal or structural abnormalities, concurrent maternal disease (e.g. chronic hypertension, renal disease, connective tissue disease) were excluded from the study. Maternal age, parity and smoking status of the mother were recorded. The presence of an early diastolic notch was recorded, the resistance index (RI) and pulsatility index (PI) measured. The lowest measurement of the indices was recorded; the means of PI and RI of the two vessels were calculated. Logistic regression analysis was performed to investigate the relationship between parity and the presence or absence of bilateral notches.
703 singleton pregnancies were examined. Of them 305 (43.4%) were nulliparous and 398 (56.6%) parous. The prevalence of the presence of bilateral notches was significantly higher in nulliparous women (64.6% vs. 77.0%, p=0.0005). The differences between the Doppler indices were not significant. Demographic characteristics and uterine artery Doppler measurements of the two groups are presented in Table 1. Nulliparity (Odds ratio=1.55; 95%CI, 1.07-2.24) and maternal age (Odds ratio=0.95; 95%CI, 0.92-0.99) were shown to independent predictors for the presence of bilateral notches. In nulliparous women, mean and lowest levels of PI and RI or the prevalence of bilateral notches did not show any significant difference after the age of 30.
Maternal age and parity did not show any significant effect on the RI and PI. However, the prevalence of early diastolic notching in the uterine artery flow waveforms was significantly higher in nulliparous women. These findings suggest that a successful pregnancy may alter the impedance in subsequent pregnancies at first trimester.
First trimester, uterine artery Doppler, parity