Transient hydrops fetalis: can it be a sign for pentasomy X?. Perinatoloji Dergisi 2011;19(2):101-101
- Başkent University Faculty of Medicine Department of Obstetrics and Gynecology Adana TR
Pınar Aytaç, Başkent University Faculty of Medicine Department of Obstetrics and Gynecology Adana TR,
Çıkar çakışması bulunmadığı belirtilmiştir.
Sex chromosomal numerical abnormalities are seen in approximately 1 out of 400 live births. However, pentasomy X is a very rare chromosomal abnormality, and it is defined by the presence of five X chromosomes instead of two. Prenatal sonographic features have rarely been described in the literature.
Here we present a case of non-immune fetal hydrops at 17th weeks of gestation. Ultrasonographic examination revealed subcutaneous edema, pleural effusion and ascites in the fetus; clinodactly of fifth finger of both hands was also present. Nuchal fold was measured as 8.1 mm. Fetal echocardiography was normal. Amniocentesis result was Pentasomy X, and hydropic signs regressed at 21 weeks of gestation.
The present case reveals that temporary hydrops of the fetus may be a sign of pentasomy X.