Pregnancy and attention deficit hyperactivity disorder. Perinatoloji Dergisi 2011;19(2):109-110
- Penn State Milton S. Hershey Medical Center Department of Obstetrics and Gynecology Penn State US
- Hacettepe University Faculty of Medicine Department of Obstetrics and Gynecology Ankara TR
Serdar Ural, Penn State Milton S. Hershey Medical Center Department of Obstetrics and Gynecology Penn State US,
Çıkar çakışması bulunmadığı belirtilmiştir.
Pregnancy outcomes of patients with a previous diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD) to date have not been evaluated as a separate group. In general, the long-term effects of the diagnosis of ADHD or its treatment are unknown. In pregnancy, neither the impact of maternal ADHD diagnosis nor treatment has been evaluated. Recent studies have suggested increased rates of ADHD-like symptoms among offspring of gestations treated with antenatal glucocorticoids (aGC) and those complicated by gestational diabetes (GDM) compounded by low socioeconomic status.
To determine the occurrence of adverse pregnancy outcomes such as prematurity, low birth weight, neonatal intensive care unit (NICU) admission, cesarean rates, and correlation with postpartum depression scores in patients diagnosed and treated for ADHD and to evaluate ADHD as a potential marker for adverse pregnancy outcomes.
Retrospective chart review and analysis of 50 deliveries including the diagnosis of ADHD delivered at Penn State Milton S. Hershey Medical Center were performed. The majority of studied patients had comorbid conditions including anxiety, depression, bipolar disorder, OCD, asthma, and substance abuse. Results: ADHD patients that delivered had rates of admission to NICU at 28% and elevated postpartum Edinburgh depression scale scores in 59%. Maternal age at delivery averaged 24 years. Gestational age at delivery averaged 37.7 weeks. Average birth weight was 3140 g. No abnormalities were noted in Apgar scores. Cesarean delivery rate was 44%.
Pregnancy complicated by the diagnosis and treatment of ADHD may be associated with adverse pregnancy outcomes. Further prospective studies are warranted. Recent associations of maternal aGC administration and GDM with increasing ADHD risk introduce the question of transgenerational ADHD and possible risk for future pregnancies.
ADHD, hyperactivity, antenatal steroids, transgenerational risk